International Organization Certifies Online Medical Information

HON, an NGO affiliate of the world health organization,
certifies web sites as providing reputable medical information.

http://newsblaze.com/story/20100113095352mcco.nb/topstory.html

SOX9 makes melanoma cells sensitive to chemo

Vincent J. Hearing
National Cancer Institute, Bethesda, Maryland, USA.

According to the report, MM cells can be made
sensitive to treatment by retinoic acid
by exposing them to SOX9.

This is research stage data, not clinical trial - level information.
 
View the PDF of this article at: https://www.the-jci.org/article.php?id=34015

--
John

Certified Reuters Insight Expert Consultant
www.newmedicineonline.com

Akt3 melanoma trigger (source of veggie treatment reports)

Akt3 is a protein active in most melanoma cells
and appears related to the spread of the disease.

ISC-4 and ISC-6 (isoselenocyanate) chemicals
derived from green veggies and modified with
selenium appear to block Akt3 activity with little
adverse effect.

This doesn't mean taking selenim and eating cabbage
are a treatment for melanoma however MM patients
often have low selenium
(and Vitamin D-3 - my information from other sources)
serum levels. So, what could it hurt until the
drugs are tested and approved?

http://www.ncbi.nlm.nih.gov/pubmed/19208796

This is one of the more sensational articles
http://www.telegraph.co.uk/scienceandtechnology/science/sciencenews/4949430/Drug-that-boosts-chemotherapy-offers-new-hope-for-skin-cancer-sufferers.html

AND
http://health.discovery.com/news/healthscout/article.html?article=624691&category=34&year=2009


--
John

Certified Reuters Insight Expert Consultant
www.newmedicineonline.com
www.15767.com

Melanoma Molec. Map Project

Good source of comprehensive drug
(http://www.mmmp.org/MMMP/public/ddd/listDDD.mmmp;jsessionid=B356AF53D513062B6C52A1645C3BE9DA)

and searchable clinical trial lists for melanoma
http://www.mmmp.org/MMMP/public/trials/listTrials.mmmp;jsessionid=B356AF53D513062B6C52A1645C3BE9DA


--
John

Certified Reuters Insight Expert Consultant
www.newmedicineonline.com

Selenium + Cruciferous Veg fight melanoma

Selenium + Cruciferous Veg fight melanoma

Recent research
http://live.psu.edu/story/37998
shows that melanoma can be fought with a combination of selenium and green vegetables including cabbage, broccoli, and others block the Akt3 protein and "signaling" network which is the root of melanoma cancer.

http://www.ncbi.nlm.nih.gov/pubmed/19235039?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum


--
John

Certified Reuters Insight Expert Consultant
www.newmedicineonline.com

7thSpace carries Vitamin D receptor Study Info

Breast and MM cancer and Vitamin D receptors
http://7thspace.com/headlines/300738/genetic_analysis_of_the_vitamin_d_receptor_gene_in_two_epithelial_cancers_melanoma_and_breast_cancer_case_control_studies.html

See my earlier blog posts for information about
Vitamin D and MM mortality.
Remember, most sunscreens promote the
destruction of Vitamin D - see
earlier postings for related scientific studies.

--
John

New Orphan Drug Designated

TransMolevular Inc (http://www.transmolecular.com/)
. has been granted orphan drug designation for 131I-TM601,
a Phase 1 clinical treatment for Stage IIb-IV melanoma.

--
John